Grignard Reaction

The Grignard Reaction Synthesis of triphenylmethanol Josh Wilson Chem 443-003 January 1,2012-February 7,2012 Introduction In this experimentation we synthesized triphenylmethanol from a Grignard reagent and an ester. To form triphenylmethanol we reacted methyl benzoate with phenylmagnesium bromide. Reaction Scheme: theory An organo metal(prenominal) compound is an original compound that contains a century-metallic bond. The metal idler be Li, Na, Mg, Cu, Pd or any other transitional metal. In this science laboratory we used Mg as our metallic portion of the organometallic compound. Organometallic compounds be special in that they cause Carbon to become a nucleophile. More specifically in this lab we used R-Mg-Br an alkyl magnesium halide to project the nucleophillic properties onto the Carbon atom, cognise as a Grignard reagent because of it founder chemist Victor Grignard. The design of Grignard reactions is to create a C-C bond, more speci fically a third or a secondary alcohol. The Grignard reagents argon usually created with the solvents anhydrous diethyl ether or THF and are very air sensitive. The Grignard reagent are very prefatory which make them very good proton acceptors. In our experiment we created a ordinal alcohol by utilise an ester and carbonyl molecule.

The ester is born-again to a ketone than immediately reacts with the Grignard reagent to give the tertiary alcohol, triphenylmethanol. Reaction machine Procedure A. Preparation of the Grignard reagent * Weigh virtually .5 g of Magnesium turnings * engage mortar and pastel to labor turnings * Put tunings into ! around layabout flaskful * Assemble machine * Prepare 2.4 mL of bromobenzene in 5 mL of anhydrous diethyl ether * Swirl mixture, than add 5mL to round bottom flask * Reflux reaction * Add .5 mL increments of the impractical response over 10 minutes B. Synthesis of Triphenylmethanol * Dissolve 1.2 mL of methyl benzoate in 5 mL of anhydrous diethyl ether *...If you call for to get a full essay, order it on our website: BestEssayCheap.com

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